Ideal system for every bacterial strain

Concentration

Im Enzymherstellungsprozess werden Ultra- und Diafiltrationsanlagen u.a. zur Produktkonzentrierung verwendet.

Der Prozessschritt Aufkonzentrieren im Detail

Biotech

Im Geschäftsfeld Biotech verfügen wir über folgende Kapazitäten:

  • 400 l/min crossflow Produktion

  • 60 l/min crossflow Pilot-Plant

Concentration in our business field

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Biotech

The Uniflux 400 (GE Healthcare) system used at Lactosan is an automated tangential or crossflow filtration system for microfiltration, ultrafiltration or diafiltration. A 5000 litre harvesting tank specially designed for the filtration system guarantees a smooth product concentration and/or buffer exchange in the enzyme production process. The feed flow rate of the system is 400 litres/min with a filter area of 112 m2.

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Get in touch with our experts

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Thomas Lautischer

Product Manager

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Further Technologies

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Filtration techniques

The  filtration system allows to remove the production organism or components thereof in the product, at the customer's request.

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DNA-depletion

DNA depletion is another optional step in the enzyme production process to increase the purity of the product.

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Fermentation

Lactosan has three complete fermentation lines which are controlled by a process control system and can be fully sterilised.

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Separation

Fermentation is followed by a concentration step using a separator.

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Homogenisation

In the homogenisation step, the biomass is broken down and the enzymes are released. 

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Precipitation

In order to increase the purity of the enzyme product or to improve subsequent filtration steps, it is possible to integrate a precipitation step into the production process.

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