Ideal system for every bacterial strain

Separation

Fermentation is followed by a concentration step using a separator. Both the pipework and the separators are CIP and SIP capable. A concentration factor of 25-30 can be achieved. The wastewater from the process is chemically and thermally inactivated.

The separation capacities in detail

Microbial Additives

Media tanks

  • 4 x 10,000 l/h production

  • 100 l/h pilot plant

Biotech

We have the following capacities in the Biotech business field.

  • 10,000 l/h production

  • 100 l/h pilot plant

Pharma

We have the following capacities in the Pharma business field.

  • 1,400 l/h production

Separation in our business areas

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Biotech

The biomass is separated from the supernatant using a sterilisable centrifuge with a capacity of 10,000 l/h. The flow rate can be adjusted between 100 - 6,000 l/h to suit the requirements of the product.

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Microbial Additives

Four nozzle separators are available for separation in the Microbial Additives plant. By using different nozzle diameters, an optimum concentration result can be achieved for specific strains and the process yield can be kept high. A closed, sterilisable piping system transports the heavy phase to the concentrate tank where special additives are added to protect the cells during the freeze-drying process and preserve viability.

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Pharma

A qualified nozzle separator is available in the pharmaceutical plant for concentration. By using different nozzle diameters, optimum concentration and therefore high yield can be achieved in the process, depending on the strain. Both the pipework and the separator are CIP and SIP capable.

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Get in touch with our experts

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Thomas Lautischer

Product Manager

Contact us

Further technologies

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Freeze drying

The aim of freeze-drying is to obtain a dried, very water-soluble product that retains the properties of the original product after the addition of water.

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Fluidised bed drying

In the Microbial Additives plant, it is possible to dry the bacterial concentrate in the fluidized bed plant as an alternative to freeze-drying.

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Mixing

After the drying and milling process, the powder is processed on the relevant powder line and the final product is mixed according to specification.

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Homogenisation

In the homogenisation step, the biomass is broken down and the enzymes are released. 

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Concentration

In the enzyme production process, ultrafiltration and diafiltration systems are used to concentrate the product and for buffer exchange respectively.

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Filtration techniques

The  filtration system allows to remove the production organism or components thereof in the product, at the customer's request.

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Grinding

After drying, further processing takes place in the respective powder line. The product flakes dried by lyophilisation are crushed in mills.

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