Ideal system for every bacterial strain
Lactosan has three complete fermentation lines which are controlled by a process control system and can be fully sterilised. The plant has a NaOH line system for pH control, but can also be supplied with NH3, KOH or acid from external tanks. Aeration with air, N2 or special gas mixtures is possible at any time. Automatic CIP/SIP cleaning steps are performed after each production run.
Our capacities:
4 Media tanks Microbial Additives
4 Media tanks Biotech
1 Media tank Pharma
We have the following production volume in the Microbial Additives division:
2 000 litres, 1 000 litres and 500 litres pre-stage fermenter
2x 1 000 litres, 1 500 litres and 50 000 litres main fermenter
We have the following production volume in the Biotech business area:
5 000 litres and 1 000 litres pre-stage fermenter
2 x 15 000 litres main fermenter
We have the following production volume in the Pharma division:
1 000 litres main fermenter
We have the following production volume in the Microbial Additives business unit:
16 litres pre-stage fermenter
700 litres, 300 litres and 150 litres main fermenter
We have the following production volume in the Biotech business area:
16 litres pre-stage fermenter
700 litres, 300 litres and 150 litres main fermenter
Fermenters with a maximum capacity of 15,000 litres are available at Lactosan Biotech. The production line consists of several pre-stage and main-stage fermenters, supplemented by media and harvesting tanks. All equipment is made of stainless steel and is controlled and monitored by a modern process control system.
The Microbial Additives facility has two completely separate fermentation lines with a maximum capacity of 50,000 litres of fermentation volume. Each production line consists of several pre and main stage fermenters, all made of stainless steel and fully sterilisable. Multiple dosing tanks allow time-controlled fed-batch production. An optimised process is developed for each bacterial strain The parameters of this strain-specific recipe are then programmed into the control system. This ensures consistently high production quality.
A fermenter with a capacity of up to 1,000 litres is available in the pharmaceutical production line, supplemented by a media tank. Automated and validated CIP/SIP cleaning steps are performed after each production run. A GMP-compliant batch record is kept for each fermentation, supplemented by parameter data from the process control system and analytical values from the QC laboratory.
Product Manager
Telephone:
+43 (0)38 62/326 02-24E-Mail:
lautischer@lactosan.at
